Publisher Drawn & Quarterly explains, "Optic Nerve 14 brings Adrian Tomine’s multifaceted, expressive cartooning to a new peak with two stories and a bonus autobiographical strip. “Killing and Dying” is about a father’s struggles to be supportive: it centers on parenthood, mortality, and stand-up comedy. “Intruders” depicts a man obsessively trying to find his way back to a former life by revisiting places he once knew. Optic Nerve 14 will appear on the twentieth anniversary of Tomine’s beloved comic book series, in whose pages the landmark graphic novel Shortcomings was first published. Each story in Optic Nerve 14 reveals new dimensions to Tomine’s unique visual sensibility and complex, character-driven stories."